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Genetic Engineering and Diseases – Gene Drive & Malaria

Kurzgesagt – In a Nutshell1 HN recommender · recommended in 1 month, 2016–2025
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explainer · general · 2016–2025 on HN

A Kurzgesagt animation on using gene drives to modify mosquitoes against malaria, and whether we should. It explains the mechanism and the ethical trade-offs.

HN links it as a clear explainer of gene drive when mosquito genetic engineering comes up.

3 comments from Hacker News

@smnscu2016-10 · in “We’re trying to stop bad mosquitoes by raising and releasing good ones”

Similar (using crispr to change the mosquitoes' genome) video from Kurzgesagt, one of my favourite Youtube channels: ▶ this video

Recommends View on HN
@gcanyon2025-03 · in “Gene drive modified mosquitoes offer new tool for malaria elimination efforts”

The idea of using gene drive on mosquitoes has been circulating for at least 8 years. [1] In that time, something like 4 million people have died of malaria, many millions more have been infected, and it is significantly impacting the economic growth of Africa. What will it take for us to pull the trigger on this? 1. ▶ this video

@chasil2022-04 · in “Results from first US trial of genetically modified mosquitoes”

The introduction of an invasive species can have an overall beneficial effect if carefully evaluated, and there is a lot that can go wrong. link It appears that a "gene drive" was introduced into the Florida Keys in this case, and that is much more targeted and specific to a species that it is intended to destroy. ▶ this video