Original Zoloft Commercial
SuperBowlSammyCited 4× on HN, 2019–2025
other · general · 2019–2025 on HN
A one-minute animated commercial for the antidepressant Zoloft, described as the original that inspired later sequels and parodies.
Mostly cited as a recognizable example of antidepressant advertising in debates about pharmaceutical marketing and the serotonin theory.
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4 comments from Hacker News
> People who having passing familiarity with neuroscience often assume that psychiatric medications work by correcting deficiencies, but this isn't true. They think this because that’s literally what the commercial for Zoloft said. [0] [0] ▶ this video
The drug industry does the same thing. Has anyone else watched a anti-depression medicine commercial and suddenly felt they are depressed? ▶ this video I mean watch this and tell me you don't want what they're selling.
>Citation required ▶ this video >"Depression may be related to an imbalance of natural chemicals between nerve cells in the brain. Prescription Zoloft works to correct this imbalance."
It’s pervasive, especially in the early days of marketing antidepressants to the general public. Example, probably the most the most recognizable anti-depressant ad ever (at least in the US): ▶ this video @ 0:20